Today, oncology is a field where 3D NLS imaging methods can also be widely applied. However, until today, the application of 3D NLS studies in patients undergoing surgery for bladder tumors also included the dynamic monitoring of the organ's condition in order to detect recurrent tumors and metastases at an early stage. The introduction of 3D NLS methods into clinical practice by Meta Hunter could completely change the view on this issue. We believe that this issue is indeed topical, since most surgical patients undergo a traumatic transurethral resection.
The application of 3D NLS studies with spectral entropy analysis, performed during surgical incision, allowed us to detect additional tumor tumors not documented by 2D NLS studies in 37% of patients. The application of 3D methods allows to clarify the extent of local spread of the neoplastic process, control the depth of bladder wall resection and reduce the risk of complications during the incision.
In general, the diagnosis and morphological verification of rectal cancer do not present difficulties. However, the degree of invasion of the organ wall cannot always be assessed by standard diagnostic methods. Conventional 2D NLS studies have been widely used as a diagnostic method for recurrent rectal cancer after organ removal. However, the initial diagnosis of the disease by 2D NLS imaging is hampered by several reasons. First, it can be explained by the fact that the rectum is only partially displayed (80% of the entire organ surface area) in a 2D NLS scan.
The application of 3D NLS imaging allows accurate differentiation of all layers of the rectal wall, thereby diagnosing the depth of tumor invasion and determining the stage of the disease using spectral entropy analysis. This method helps to detect lymph node changes larger than 1.5 mm in pararectal lymph node metastatic lesions. During monitoring of preoperative radiotherapy, 3D NLS imaging helps to accurately detect a decrease in tumor size, identify changes in its structure, related to medical pathological morphology, identify a decrease in tumor infiltration of pararectal tissues. Therefore, 3D NLS imaging can be considered as a preliminary diagnostic method for rectal cancer. It allows the therapist to solve the most important diagnostic problems, related to identifying the length of the tumor process, the extent of local spread of the tumor and monitoring the efficiency of preoperative treatment conducted. In organ-sparing surgery, 3D NLS imaging can be used as an effective method for early diagnosis of recurrent tumors in the anastomotic zone.
In conclusion, as a result of the short nature of modern 3D NLS imaging methods, we want to emphasize that this method can effectively achieve goals such as detecting tumor changes, determining the stage of the disease and conducting a qualitative evaluation of treatment.
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