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The study included 78 men and women with a high body mass index (BMI) who were classified as overweight or obese, and 105 men and women with a low BMI.
BMI is a measure of body fat based on height and weight. A higher BMI does not always indicate higher body fat.
They also underwent three MRIs to assess brain structure and function, as well as connectivity between different brain regions.
The results showed that specific changes in brain connectivity were associated with higher BMI in both men and women.
This includes "changes in many regions of the brain in response to food or food-related cues," which have been linked to early life trauma, the researchers wrote.
They also found that women with high BMI showed changes in connectivity associated with greater anxiety and lower resilience compared with men with high BMI.
Other connectivity changes in women with high BMI suggest that women may have difficulty integrating emotions with action-oriented goal planning, the researchers wrote. This could lead to women being more prone to "emotional binge eating" compared with men, they said.
In addition, certain brain changes suggest that women with a high BMI may be more susceptible to the sight, smell and taste of ultra-processed foods.
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