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Biophilia Tracker technology assesses changes in various skin conditions

Literature analysis shows that NLS-skin research is commonly used in various oncological diseases. To study skin tumors, two- and three-dimensional NLS imaging can be applied. In most cases, the tumors appear as areas of increased chromogenicity, more or less separated from the dermis. It is not possible to define the histological characteristics of tumors based on NLS imaging alone.

For the differential diagnosis of skin tumors such as hemangioma or melanoma, the modality of ultramicroscanning with spectral entropy analysis (SEA) can be successfully applied.

Malignant melanoma can be studied using NLS imaging. The melanomas in the NLS study were spindle-shaped, uniform in structure, and clearly separated from the surrounding tissue. We noted a high accuracy in tumor size assessment, which was confirmed by comparison with data obtained from NLS studies of tumors before surgical intervention and by histological testing after surgery. According to other data, although tumors are well visualized in NLS graphical studies, the main problem is distinguishing the tumor parenchyma from the surrounding inflammatory infiltrate because they appear as a single highly chromogenic structure. Therefore, the size of some tumors may be exaggerated in NLS studies. As a study by Ulrich J. et al. showed that the accuracy of tumor size assessment is significantly improved if we exclude tumors with extensive inflammatory infiltrates or nevus-associated melanomas from the analysis when applying SEA.

Thanks to modern NLS technology with Biophilia Tracker, changes in various skin diseases can be assessed more accurately; it not only improves diagnosis and starts treatment at the right time, but also ensures control of treatment efficiency.