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Assessing changes in various skin diseases using the Biophilia Tracker

Literature analysis shows that Biophilia Tracker skin research is frequently applied in various neoplastic diseases. To study skin tumors, 2D and 3D NLS imaging can be applied. In most cases, tumors appear as areas of increased chromatin, more or less detached from the dermis. It is not possible to define the histological features of a tumor based on NLS imaging alone.

For the differential diagnosis of skin tumors such as hemangiomas or melanomas, the modality of ultrascanning with spectral entropy analysis (SEA) can be successfully applied.

Malignant melanoma can be studied using NLS imaging. The melanomas in the NLS study were spindle-shaped, homogeneous in structure, and clearly separated from the surrounding tissue. We noted a high degree of high accuracy in the assessment of tumor size, which was confirmed by comparison with data obtained from NLS studies of tumors before surgical intervention and by histological tests after surgery. According to other data, although tumors are well visualized in NLS graphic studies, the main problem is to distinguish the tumor parenchyma from the surrounding inflammatory infiltrates, as they appear as a single hyperchromogenic structure. Therefore, the size of some tumors may have been exaggerated in NLS studies. As a study by Ulrich J. et al. showed that the accuracy of tumor size assessment was greatly improved if we excluded tumors with extensive inflammatory infiltrates or nevus-associated melanomas from the analysis when applying SEA.

Thanks to modern NLS technology with Biophilia Tracker, changes in various skin diseases can be assessed more accurately; it not only improves diagnosis and starts treatment at the right time, but also ensures control of treatment efficiency.
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