Portable Handheld Laser Therapy Device is effective in repairing tissues and slowing down inflammatory reactions.

Using the optimal lighting parameters of the Portable Handheld Laser Therapy Device - red light 630 nm (15 mW/cm2, 4 J/cm2) and near-infrared light 850 nm (10 mW/cm2, 4 J/cm2), compare red light and near Infrared light stimulation stimulates the proliferation of bone marrow mesenchymal stem cells cultured in vitro and its mechanism of promoting proliferation.
The results showed that both groups of stimulation parameters can promote stem cell proliferation. On the 7th day, the number of cells in the near-infrared light experimental group increased by 43.48% compared with the control group, while the red light experimental group increased by 20.95%. In terms of the number of cell communities, the number of cells in the near-infrared light group was higher than that of the control group. The number of communities is 17.38% more than that of red light. There were very different results when it came to reactive oxygen species (ROS). The near-infrared light group increased ROS production by 36.9%, but the red light group suppressed it by 27.5%. In terms of gene expression, neither red light nor near-infrared light significantly activated heat shock protein 70; in terms of cyclin D1 expression, red light showed the highest expression 1 hour after stimulation, while near-infrared light could increase cyclin immediately after stimulation. D1 performance.
Red light will significantly improve the performance of SOD1 and SOD2 6 hours after illumination, while near-infrared light can significantly increase the performance of SOD1 1 hour after illumination, and SOD2 will be significantly manifested immediately after the end of stimulation. ALP performance is not affected by red light and near-infrared light. Mitochondrial membrane potential increased significantly after exposure to light; and cell cycle analysis showed that both light sources can promote stem cells to enter the S phase.
Ultimately, it was shown that the Portable Handheld Laser Therapy Device can induce biological effects and perform biological regulation to repair tissues and slow down inflammatory reactions.